AXONDAO

OVERVIEW

Your Voice Reflects Your Mind. We Decode It to Understand Microdosing Effects.

This study will explore the relationship between speech, mood, creativity and cognitive functions in psychedelic microdosers. Specifically it will investigate whether microdosing psilocybin or LSD results in unique speech biomarker patterns during and after use.

Given the antidepressant properties of psychedelics and their effects on mood, creativity and cognitive flexibility, these elements will be evaluated at baseline, during, and after psychedelic microdosing. This will be the first study to analyze speech dynamics in relation to psychedelic states and their impact on mood, creativity, insight, and cognition.

Participants will complete neuropsychological tests, verbal tasks, and surveys via a web app, ensuring accessibility and diversity. This large-scale, anonymous study aims to measure the real-world effects of psychedelic microdosing on mood and cognition, potentially uncovering new mechanisms of action and providing preliminary evidence for further research.

Recent findings suggest that microdosing can affect speech patterns. This study aims to validate these results in a larger sample and correlate speech changes with psychotherapeutic benefits. Speech biomarkers, derived from speech patterns, can offer objective insights into mental and emotional states, enhancing the understanding of benefits of microdosing for mental well-being and monitoring the effectiveness of microdosing schedules.

Data will be analyzed using advanced voice analytics and machine learning, with the goal of identifying voice biomarkers which can predict therapeutic effects and effective microdosing regimes.

This study will explore the relationship between speech, mood, creativity and cognitive functions in psychedelic microdosers. Specifically it will investigate whether microdosing psilocybin or LSD results in unique speech biomarker patterns during and after use.

Given the antidepressant properties of psychedelics and their effects on mood, creativity and cognitive flexibility, these elements will be evaluated at baseline, during, and after psychedelic microdosing. This will be the first study to analyze speech dynamics in relation to psychedelic states and their impact on mood, creativity, insight, and cognition.

Participants will complete neuropsychological tests, verbal tasks, and surveys via a web app, ensuring accessibility and diversity. This large-scale, anonymous study aims to measure the real-world effects of psychedelic microdosing on mood and cognition, potentially uncovering new mechanisms of action and providing preliminary evidence for further research.

Recent findings suggest that microdosing can affect speech patterns. This study aims to validate these results in a larger sample and correlate speech changes with psychotherapeutic benefits. Speech biomarkers, derived from speech patterns, can offer objective insights into mental and emotional states, enhancing the understanding of benefits of microdosing for mental well-being and monitoring the effectiveness of microdosing schedules.

Data will be analyzed using advanced voice analytics and machine learning, with the goal of identifying voice biomarkers which can predict therapeutic effects and effective microdosing regimes.

OVERVIEW

Your Voice Reflects Your Mind. We Decode It to Understand Microdosing Effects.

This study will explore the relationship between speech, mood, creativity and cognitive functions in psychedelic microdosers. Specifically it will investigate whether microdosing psilocybin or LSD results in unique speech biomarker patterns during and after use.

Given the antidepressant properties of psychedelics and their effects on mood, creativity and cognitive flexibility, these elements will be evaluated at baseline, during, and after psychedelic microdosing. This will be the first study to analyze speech dynamics in relation to psychedelic states and their impact on mood, creativity, insight, and cognition.

Participants will complete neuropsychological tests, verbal tasks, and surveys via a web app, ensuring accessibility and diversity. This large-scale, anonymous study aims to measure the real-world effects of psychedelic microdosing on mood and cognition, potentially uncovering new mechanisms of action and providing preliminary evidence for further research.

Recent findings suggest that microdosing can affect speech patterns. This study aims to validate these results in a larger sample and correlate speech changes with psychotherapeutic benefits. Speech biomarkers, derived from speech patterns, can offer objective insights into mental and emotional states, enhancing the understanding of benefits of microdosing for mental well-being and monitoring the effectiveness of microdosing schedules.

Data will be analyzed using advanced voice analytics and machine learning, with the goal of identifying voice biomarkers which can predict therapeutic effects and effective microdosing regimes.

STUDY OBJECTIVES

Understanding the psychological and cognitive effects of psychedelic microdosing through voice.

Voice analytics meets psychedelic science to decode mood, cognition, and creativity shifts.

The PSYLOSYS project is designed to investigate how regular microdosing of psychedelics—such as psilocybin and LSD—affects individuals' psychological states, cognitive performance, and vocal expression. This study aims to:

Examine the effects of microdosing on mood, cognition, and speech:
By collecting self-reported data, neuropsychological assessments, and verbal recordings, the study observes how microdosing influences emotional regulation, mental flexibility, attention, and verbal fluency over time.

Identify novel vocal biomarkers linked to microdosing states:
Using AI-powered voice analysis, the study will uncover measurable changes in vocal patterns (tone, pace, rhythm, and articulation) that may correlate with psychedelic-induced neuropsychological shifts.

Correlate speech changes with mood, cognition, and creativity:

Participants' voice data will be cross-analyzed with mood tracking and creativity tasks to assess whether specific vocal cues align with reported changes in mental state or creative thinking.

Assess the potential of voice analytics as a monitoring tool:
The ultimate goal is to evaluate whether speech analysis can serve as a reliable, non-invasive method for tracking therapeutic responses, paving the way for future integration into personalized mental health care and psychedelic-assisted therapy programs.