This study aims to explore the relationship between vocal expressions, mood, and cognitive functions during psychedelic experiences. It will specifically investigate whether individuals consuming psilocybin and ketamine, through either single doses or a microdosing regimen, demonstrate unique speech biomarker patterns during and after psychedelic consumption
Additionally, the research will assess how these vocal biomarkers correlate with depression severity, measured by scores on the MADRS scale. Given the well-documented antidepressant properties of psychedelics, and their capacity to alter mood, enhance creativity, cognitive flexibility, and induce profound or mystical experiences, these elements will be evaluated among participants before, during, and after their psychedelic experiences. To the best of the researchers' knowledge, this study will be the first to analyze speech dynamics within psychedelic states and its potential links to changes in mood, creativity, insight, and cognitive processes.
The research team plans to conduct an extensive survey with a broad, global participant base, using a web application that facilitates at-home completion. Participants will undergo established neuropsychological assessments, engage in verbal tasks, respond to relevant survey questions, and provide a voice sample. The study's online and anonymous format aims to increase its accessibility and diversity, enhancing the measurement of the "real-world" impacts of psychedelics on mood and cognition.
Risk management and compliance, when approached strategically, have the potential to go beyond mitigating threats.
Utilizing AI to identify early indicators of adverse health conditions through voice analysis
Predictive AI capabilities enables swift action, allowing individuals to address potential health issues well in advance
Leveraging blockchain technology ensures that voice data is secure, unalterable, and fully traceable, empowering patients with complete ownership and control over who accesses their data for research purposes
Granting users full control over their data fosters trust and encourages long-term engagement with the decentralized science projects